donnatal
What is Donnatal?
Donnatal Extentabs is an extended release anti-spasmodic drug. This means that it is designed to relax the muscles in the gut wall and reduce spasms and pain, and to do this over a longer period of time than other anti-spasmodic medications.
What symptoms does it treat?
Donnatal is designed to treat the general symptoms of IBS such as abdominal pain and diarrhea.
How is it taken?
Donnatal comes in tablet form.
REVIEWS OF DONNATAL
Review by Cindy 
I've been suffering with IBS-D for about three months now. After trying fiber, having a colonoscopy and getting over a fissure, my doctor prescribed Donnatal, one tablet (48mg extended release) twice a day. After looking at the ingredients I knew I wouldn't be able to take it very well. I take one a day around 11:30am. By 2pm I'm falling asleep at my desk and by 4pm my mouth is so dry I can hardly swallow. Then about 6pm I'm jittery and cranky. I haven't had any painful diarrhea since I started taking it though. I'm not sure what to do.
Review by Laurie 
I have IBS-D which sometimes gets bad enough that I lose weight and suffer from malnutrition. I take several medications for this, including an anti-cholinergic for any episodes of bad intestinal cramping (the diarrhea is a daily, frequent thing, with or without bad cramps). Lately my cramping has seemed to require more than what I normally had been taking. Additionally, there has recently been a hyoscyamine/Levsin shortage. Consequently, my GI doc's office put me on Donnatal, one pill four times a day.
The first day, I took a half a tablet in the morning. I fell asleep, which felt more like falling unconscious. When I woke up hours later, I felt groggy, dizzy, and trippy (spacing out a lot). This feeling lasted for over 12 hours. Next day, I started having pain again so I took a quarter of a tablet. Same kind of symptoms, but they were less severe and lasted a shorter time.
Next dose (about eight hours later) I took an eighth of a tablet. Still spacey but better. However, even on an eighth of a tablet there is no way at all I could drive or work on this drug. I had a hard time walking up and down stairs or making dinner. I suspect much of this is the barbiturate component of the medication since I've taken many (many) hyoscyamine/Levsin tablets in a given day and not experienced anything at all like this reaction.
Review by Doug 
I have suffered from IBS for 20 years and the only thing that works is Donnatal. I still have horrible episodes where I can barely function, in fact, I am in the midst of one right now. My provider has shifted to the generic form of Donnatal and it does not seem as effective. I pray for anyone who suffers with this horrible disorder.
Review by Alice
During pregnancies I would have been sick the whole time if it had not been for Donnatal. Now, I’m 77 years old. Suddenly diarrhea became uncontrollable and reflux was eating up my esophagus. After my doctor prescribed Donnatal for me I was no longer miserable. I’m no longer sick to my stomach, I no longer have awful nightmares, seldom have a painful attack of diarrhea and I'm not afraid to go where and when I choose. My sleep and even my naps are so much more comfortable and pleasant.
Review by Lori
I have been taking Donnatal for about one week now. I have suffered immensely with IBS-D for as long as I can remember. I am 32, and since having my last two children (c-sections) and my gallbladder out two months ago, I having been suffering to the point of being paranoid to leave my house. I am afraid to go to work, or out with my small children in case of an attack.
I am just so utterly depressed about this illness. It is not only terribly painful (at times, I really think that my family will find me dead on the toilet), but it is so humiliating and isolating. Only people who experience it actually understand. The Donnatal seems to help take the edge off the pain, but it makes me very tired, and again I have small children to care of.
I have used Lomotil in the past, and Bentyl and Nulev, but all seem to be temporary fixes. I don't like the thought of taking these pills like candy every day. But I am getting to the point that if I want to have any decent social life, I will have to be dependent on these drugs. It seems like my diarrhea has gotten 10 times worse since my gallbladder was removed. I had no idea this was a common side effect of the surgery.
Anyway, I read the other reviews and just want to cry my eyes out because I feel everyone's pain, and just can't believe there is nothing anyone can really do to cure this problem. My prayers are with everyone out there, we are all just longing to live our lives without this painful, embarrassing, debilitating disorder. I feel like it has taken my spirit away from me.
Review by Stephanie 
My doctor diagnosed me with IBS almost six months ago. I had had my gallbladder removed six months prior, and was still having no relief from the cramping and nausea. My doctor prescribed Donnatal and Valium (5mg) twice a day. After just a few days, I began to feel better. I now take them together only once a day, and still feel great. I cannot say enough good things about this drug...it has changed my life. Another good thing....the generic form is very affordable at less than $10.
Review by Diane
My life has gradually been overtaken by IBS. A gastroenterologist gave me Donnatal, two tablets three times a day, two months ago. In general, this drug has lowered the severity of the abdominal pain that I had been having. Formerly I had level eight pain for an hour or more per day; now the Donnatal has reduced that to about a level five pain and shortened the duration of the attacks most of the time.
Last month I was pain-free for nine days out of 30. With the Donnatal I get fewer attacks per day. However, taking Donnatal 30-60 minutes before each meal does not guarantee I will not get a pain attack. The attacks are unpredictable for the most part.
However, Donnatal has had some beneficial side effects for me: I fall asleep quickly and sleep like a baby most nights, whereas previously I slept fitfully. I also have less problems with acid reflux since taking Donnatal. One unusual benefit from this medication is that previously I was embarrassed by sweating excessively (I got soaked just from a little light garden work), but now that doesn't happen. And one wonderful side effect is that since I have been taking Donnatal, my compulsive eating and bulimia has stopped! I have no desire to overeat or purge. What a blessing in disguise!
Do you suffer from IBS? Have you tried Donnatal? Please send in your review.